{"id":124,"date":"2020-09-26T00:00:00","date_gmt":"2020-09-26T07:00:00","guid":{"rendered":"http:\/\/moleculesatmidnight.com\/?p=124"},"modified":"2020-09-28T11:02:14","modified_gmt":"2020-09-28T18:02:14","slug":"anatomy-of-a-virus","status":"publish","type":"post","link":"http:\/\/moleculesatmidnight.com\/?p=124","title":{"rendered":"Anatomy of a Virus"},"content":{"rendered":"\n<p class=\"has-background\" style=\"background-color:#ebebeb\"><span style=\"color:#001a7a\" class=\"has-inline-color\">In light of all going on in the world, I thought it was time to delve into the anatomy of a virus.&nbsp; Our knowledge of a virus begins in 1935 when Wendell Stanley studied a crystalized tobacco virus.&nbsp; Today, we\u2019ll be taking a look at each of its structures, mechanisms, and tricks that allow it to infect a host by summarizing a chapter of the textbook <em><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK21523\/\">Molecular Cell Biology<\/a>.<\/em><\/span><\/p>\n\n\n\n<p class=\"has-background\" style=\"background-color:#ebebeb\"><span style=\"color:#001a7a\" class=\"has-inline-color\">Because viruses cannot reproduce independently, they require a host cell and utilize its internal machinery to replicate.&nbsp; All viruses do have RNA or DNA, which are long strands of genetic material falling under the category of nucleic acids.&nbsp; RNA is composed of a single strand of nucleotides, while DNA is organized into the commonly recited shape of a double helix.&nbsp; Simple viruses have genetic material that codes for four proteins, but more developed viruses can code for up to two hundred proteins.&nbsp; Viruses use a host cell\u2019s transcription and translation system to replicate their own genetic material.<\/span><\/p>\n\n\n\n<p class=\"has-text-color has-background\" style=\"background-color:#ebebeb;color:#001a7a\">The genome is protected by a capsid, a geometrically shaped container that stores the RNA or DNA.&nbsp; This capsid contains enzymes and glycoproteins that help the virion break past the host cell membrane as well.<\/p>\n\n\n\n<p class=\"has-text-color has-background\" style=\"background-color:#ebebeb;color:#001a7a\">Surrounding the capsid, there will sometimes be a lipid envelope, found generally on animal viruses, that will contain glycoproteins as well.&nbsp;<\/p>\n\n\n\n<p class=\"has-text-color has-background\" style=\"background-color:#ebebeb;color:#001a7a\">A virus will enter the cell via its cell membrane, utilizing the glycoproteins on either the capsid or the envelope.&nbsp; Glycoproteins are specifically shaped proteins that fit into proteins on the host cell\u2019s membrane.&nbsp; They function as a key, enabling the virus to put its genetic material into the cell.&nbsp; Viruses that only contain glycoproteins able to access bacteria are called bacteriophages, while those that can infect animals and plants are called animal\/plant viruses.&nbsp;<\/p>\n\n\n\n<figure class=\"wp-block-image size-large\"><img loading=\"lazy\" decoding=\"async\" width=\"500\" height=\"348\" src=\"http:\/\/moleculesatmidnight.com\/wp-content\/uploads\/2020\/09\/f-d_779f166e7662c1c31c5c46df450ef22c5ceab04311ec4d6f82dbbc0dIMAGE_THUMB_POSTCARD_TINYIMAGE_THUMB_POSTCARD_TINY.jpg\" alt=\"\" class=\"wp-image-125\" srcset=\"http:\/\/moleculesatmidnight.com\/wp-content\/uploads\/2020\/09\/f-d_779f166e7662c1c31c5c46df450ef22c5ceab04311ec4d6f82dbbc0dIMAGE_THUMB_POSTCARD_TINYIMAGE_THUMB_POSTCARD_TINY.jpg 500w, http:\/\/moleculesatmidnight.com\/wp-content\/uploads\/2020\/09\/f-d_779f166e7662c1c31c5c46df450ef22c5ceab04311ec4d6f82dbbc0dIMAGE_THUMB_POSTCARD_TINYIMAGE_THUMB_POSTCARD_TINY-300x209.jpg 300w\" sizes=\"auto, (max-width: 768px) 680px, 560px\" \/><figcaption><span style=\"color:#515151\" class=\"has-inline-color\"><em>Can you identify all the structures above and their functions? (p.c <a href=\"https:\/\/www.ck12.org\/book\/ck-12-biology-advanced-concepts\/section\/11.22\/\" data-type=\"URL\" data-id=\"https:\/\/www.ck12.org\/book\/ck-12-biology-advanced-concepts\/section\/11.22\/\">cK-12<\/a>)<\/em><\/span><\/figcaption><\/figure>\n\n\n\n<div style=\"height:50px\" aria-hidden=\"true\" class=\"wp-block-spacer\"><\/div>\n\n\n\n<p class=\"has-text-color has-background\" style=\"background-color:#ebebeb;color:#001a7a\">That&#8217;s it for this week! Check back in next time for my opinions on the best study music, as well as some of my favorite playlists to listen to while I work.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>In light of all going on in the world, I thought it was time to delve into the anatomy of a virus.  Our knowledge of a virus begins in 1935 when Wendell Stanley studied a crystalized tobacco virus.<\/p>\n","protected":false},"author":3,"featured_media":126,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[46],"tags":[12,51,14],"class_list":["post-124","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-science","tag-anatomy","tag-quarantine","tag-science"],"_links":{"self":[{"href":"http:\/\/moleculesatmidnight.com\/index.php?rest_route=\/wp\/v2\/posts\/124","targetHints":{"allow":["GET"]}}],"collection":[{"href":"http:\/\/moleculesatmidnight.com\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"http:\/\/moleculesatmidnight.com\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"http:\/\/moleculesatmidnight.com\/index.php?rest_route=\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"http:\/\/moleculesatmidnight.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=124"}],"version-history":[{"count":0,"href":"http:\/\/moleculesatmidnight.com\/index.php?rest_route=\/wp\/v2\/posts\/124\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"http:\/\/moleculesatmidnight.com\/index.php?rest_route=\/wp\/v2\/media\/126"}],"wp:attachment":[{"href":"http:\/\/moleculesatmidnight.com\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=124"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"http:\/\/moleculesatmidnight.com\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=124"},{"taxonomy":"post_tag","embeddable":true,"href":"http:\/\/moleculesatmidnight.com\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=124"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}